Connect with us

News

Study shows booster shot after 6 to 12 months likely to provide best protection from COVID-19, Pfizer says

Pfizer and BioNTech have released initial data from a study on booster shots for their COVID-19 vaccine, saying a third dose delivered about six months after the second shot has shown neutralization titers are five to 10 times higher than after two primary doses.

The companies said they expect to publish “more definitive data” soon and submit the Food and Drug Administration “in the coming weeks.”

Pfizer said real-world evidence from Israel showed a decrease in efficacy about six months after people were fully vaccinated.

“While protection against severe disease remained high across the full 6 months, the observed decline in efficacy against symptomatic disease over time and the continued emergence of variants are key factors driving our belief that a booster dose will likely be necessary to maintain highest levels of protection,” Pfizer said in a statement.

MORE: How COVID-19 booster shots could help in global fight against the virus

The FDA and Centers for Disease Control and Prevention released a joint statement Thursday evening pumping the brakes on the need for a booster shot yet, and encouraged people to get vaccinated in general. Less than 50% of the U.S. is fully vaccinated at this time.

“Americans who have been fully vaccinated do not need a booster shot at this time,” the agencies said in the statement. “FDA, CDC, and NIH (National Institutes of Health) are engaged in a science-based, rigorous process to consider whether or when a booster might be necessary.”

Additionally, the companies are working on materials with a plan to test a new vaccine construct based on the delta variant — with plans to start clinical trials in August.

“While we believe a third dose of BNT162b2 has the potential to preserve the highest levels protective efficacy against all currently known variants including Delta, we are remaining vigilant and are developing an updated version of the Pfizer-COVID-19 vaccine that uses a new construct based on the B.1.617.2 lineage, first identified in India and also known as the Delta variant,” the companies said in a statement.

“The companies are already producing clinical trial material and anticipate beginning clinical studies in August, subject to regulatory approvals,” Pfizer and BioNTech added.

PHOTO: A health care worker holds a vial of the Pfizer/BioNtech COVID-19 vaccine at Memorial Healthcare System in Miramar, Florida, on Dec. 14, 2020. (Chandan Khanna/AFP via Getty Images)
PHOTO: A health care worker holds a vial of the Pfizer/BioNtech COVID-19 vaccine at Memorial Healthcare System in Miramar, Florida, on Dec. 14, 2020. (Chandan Khanna/AFP via Getty Images)

Moderna, the maker of the only other authorized mRNA vaccine in the U.S., has made similar statements about the need for booster shots in the past.

“Booster shots will be needed as we believe the virus is not going away,” Moderna CEO Stephane Bancel said during a first-quarter earnings call to investors in early May.

MORE: US health agencies will decide if COVID-19 booster shots are needed – not vaccine companies

It will be up to the FDA and the Centers for Disease Control and Prevention to determine if and when booster shots will be allowed, recommended and made available.

“Clearly, the pharmaceutical companies have an economic incentive, particularly the ones who have vaccines that are for profit,” Dr. Dan Barouch, director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center, told ABC News in late May. “We want the decision to be made based on public health solely and [not] on economic incentives of the companies.”

ABC News’ Anne Flaherty, Arielle Mitropoulos, Dr. Deepak Ramanathan and Sony Salzman contributed to this report.

Study shows booster shot after 6 to 12 months likely to provide best protection from COVID-19, Pfizer says originally appeared on abcnews.go.com

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published.

News

Pop mogul Simon Cowell was a racing flop with ‘awful’ £35,000 horse he owned with Ant and Dec – that didn’t win a penny

SIMON COWELL conquered the music world – but his foray into racing ended in disaster with an ‘awful’ £35,000 horse he owned with Ant and Dec.

The music mogul, 62, has done it all with bands like One Direction, Little Mix and solo acts Olly Murs and James Arthur, to name but a few.

Cowell owned an 'awful' £35,000 horse with Ant and Dec - but the runner didn't win a single penny in six races

5

Cowell owned an ‘awful’ £35,000 horse with Ant and Dec – but the runner didn’t win a single penny in six racesCredit: PA:Press Association
Cowell remains a massive racing fan and loves Royal Ascot and the Epsom Derby

5

Cowell remains a massive racing fan and loves Royal Ascot and the Epsom Derby

His Syco label – plus shows such as Britain’s Got Talent – have dominated the entertainment industry and brought him an estimated net worth of £385m.

A lover of Royal Ascot and the Epsom Derby, he looked perfectly poised to strike a knockout blow in the world of thoroughbreds.

But it turns out his runner was far from No1 in the charts – and never even finished better than fifth during a doomed six-race career.

Things looked promising at the start.

Named It’s A Yes From Me, the runner was trained with the respected James Fanshawe and sent off at 8-1 for his first race in June 2014.

But coming last of five by 13-and-a-half lengths was unfortunately about as good as it got for the gelding.

A month’s rest followed before he was sent off at 40-1 in a six-furlong sprint at Doncaster.

But there he could only manage fifth again, and it was same at Redcar the next month.

‘Dreadfully slow’

By October that year – with further finishes of sixth and tenth – It’s A Yes From Me came second-last in a one-mile race at Kempton.

One analysis of the race warned punters the horse was ‘one to tread carefully’ with.

Well, Cowell and Ant and Dec took that advice to heart as they never raced him again.

The horse was penniless from six races, never finishing high enough to recoup some of that £35,000 investment.

It’s doubtful Cowell, with hundreds of millions in the bank, lost any sleep over that.

But Ant and Dec revealed just how bad things has got with the horse during an interview last year.

Dec said of It’s A Yes From Me: “It was awful, it was a dreadfully slow horse.

“It wasn’t a racehorse it was just a horse, because it didn’t race.

“Every time we got to the BGT studio Simon would say, ‘I keep paying stable fees on this horse, but I’ve never seen it run’.”

Cowell originally wanted to name the nag after himself, but they settled on It’s A Yes From Me when they bought it in 2013.

‘It was awful’

Dec revealed its eventual fate: “I think it got rehomed.”

Of course it’s not all been bad for Cowell at the races.

He was one of the exclusive few at the Epsom Derby in June, having a great time with partner Lauren Silverman and Piers Morgan.

And two weeks later he was at Royal Ascot – where he first discovered his love of racing.

Cowell told SunSport’s Matt Chapman during a chat at Epsom: “I’ve got my son Eric with me today.

“My mum and dad years ago used to take me to Ascot and I was probably about his age – seven or eight.

Cowell with partner Lauren at Epsom earlier this year

5

Cowell with partner Lauren at Epsom earlier this yearCredit: Getty
It's A Yes From Me trails behind in last during one of his six races

5

It’s A Yes From Me trails behind in last during one of his six races
The music supremo tweeted about his horse's bad start... which never got much better

5

The music supremo tweeted about his horse’s bad start… which never got much better

Most read in Horse Racing

“So the fact I can now bring him to the races as well is brilliant. It brings back a lot of good memories.

“Making TV shows is my passion. But racing is actually my second passion.”

He hasn’t made that passion the money-maker his music label is, but don’t rule out Cowell staging his own comeback at the track in the near future.

FREE BETS GET OVER £2,000 IN SIGN UP OFFERS HERE

Commercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to The Sun. 18+. T&Cs apply. Begambleaware.org


Remember to gamble responsibly

A responsible gambler is someone who:

  • Establishes time and monetary limits before playing
  • Only gambles with money they can afford to lose
  • Never chases their losses
  • Doesn’t gamble if they’re upset, angry or depressed
  • Gamcare – www.gamcare.org.uk
  • Gamble Aware – www.begambleaware.org

Commercial content notice: Taking one of the bookmaker offers featured in this article may result in a payment to The Sun. 18+. T&Cs apply. Begambleaware.org


Remember to gamble responsibly

A responsible gambler is someone who:

  • Establishes time and monetary limits before playing
  • Only gambles with money they can afford to lose
  • Never chases their losses
  • Doesn’t gamble if they’re upset, angry or depressed
  • Gamcare – www.gamcare.org.uk
  • Gamble Aware – www.begambleaware.org
Continue Reading

News

Minnesota wildfire doubles in size, creates its own weather

A wildfire in northeastern Minnesota more than doubled in size Tuesday, growing to more than 19,000 acres, after it produced pyrocumulous clouds that generated lightning and even raindrops, fire officials said.

The Greenwood Fire’s growth, most of which happened Monday afternoon, prompted firefighters to leave McDougal Lake, about 80 miles south-southwest of Duluth, officials said. Authorities fear that structures might have been destroyed or damaged.

“We had crews embedded, and as this fire took off, it was quite an effort to communicate with forces on the ground so they could get out,” said federal fire incident spokesman Clark McCreedy.

The pullout was a success, and no injuries were reported. However, downed trees and necessary cleanup mean crews have been unable to assess damage around the lake, McCreedy said.

In addition to the firefighter pullout, 159 dwellings were evacuated Monday, according to an update from the National Wildfire Coordinating Group. Cabins, homes and recreational sites remain under threat, the group said.

Patrick Prochaska, a Minneapolis resident who built a cabin near McDougal Lake in 2012, told NBC affiliate KARE that he watched via security camera as flames mostly bypassed his property Monday, causing minor damage.

“I was feeling very scared,” he said. “At the same time, I could see that it was not doing anything to the house, and it was kind of reassuring.”

The fire in and north of Superior National Forest has mostly performed according to the weather, fire officials said. On Monday, with dry fuel on the ground and temperatures in the high 80s, it was an expanding inferno punctuated by strobes of lightning.

“The winds were drawn into the fire from all directions,” the incident’s fire behavior analyst, Michael Locke, said in a video update Tuesday. “It created what we call pyrocumulous clouds. And really high in the atmosphere … you’d see a thunderstorm, and in fact they went high enough to produce a few sprinkles of rain and even some lightning.”

Temperatures dipped into the mid-70s Tuesday, and the blaze mellowed. “The real story was cloud cover and cooler temperatures,” McCreedy said.

More of the same, and possibly rain, was in the forecast, giving officials hope that they might be able to close the book on an unusually active and dry fire season in Minnesota.

Experts have said climate change has set the stage for extreme weather, including an increase in the frequency and intensity of wildfires in the Northern Hemisphere.

Firefighters — 426 were assigned to the Greenwood event — have been confronted with “prolonged, severe drought,” making parts of Minnesota look like the fire-prone West this summer, McCreedy said.

The Greenwood Fire, which was detected Aug. 15, is believed to have been sparked by lightning.

So far, firefighters have scored no containment, and areas including McDougal Lake, Sand Lake and the Highway 2 corridor have been under mandatory evacuation orders. The federal Boundary Waters Canoe Area Wilderness was closed Saturday “due to active and increasing fire activity, extreme drought, limited resources,” the National Forest Service said in a notice.

Officials set a goal of Sept. 1 for full containment.

“We’re probably going to get more of that moderating weather for the rest of the week,” McCreedy said. “That opens the door for fire crews to make progress on the ground.”

Continue Reading

News

Hiker survives grizzly bear attack at Denali National Park

A tourist from Indiana was attacked and injured by a grizzly bear at Denali National Park and Preserve in Alaska on Monday night, park officials said.

The 55-year-old tourist, whose name was not released, was hiking alone in dense fog in the Thoroughfare Pass area when a mother bear and multiple cubs charged him from nearby bushes, the National Park Service said in a statement Tuesday.

He had puncture wounds to a calf, his left ribs and his left shoulder, the agency said.

The victim used bear spray that might have cut the attack short, the park service indicated. He walked 1.5 miles to a visitor’s center where “medical personnel” vacationing at Denali treated him as a park bus driver called 911, it said.

The hiker was taken to a medical center near the park before he was transferred to Fairbanks Memorial Hospital, about 120 miles away, park officials said. He was stabilized at the Fairbanks hospital, they said.

“Due to the apparent defensive nature of this attack, there are no plans to locate the bear involved,” the park service said. “Female bears with cubs are naturally defensive of their young, especially when surprised. There is no indication that this bear is unusually dangerous.”

Grizzly bears are federally protected as a threatened species in the lower 48 states. According to the National Wildlife Federation, fewer than 1,500 grizzlies are left in the lower 48, but they thrive, comparatively, in Alaska, where they have a population of about 31,000.

The backcountry area of the attack is closed for one week as a precaution, the park service said.

Continue Reading

Trending

Copyright © 2021 Insight Global.